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Batroxobin is a serine protease that reduces fibrinogen levels and was originally extracted from the venom of Bothops atrox (Common Lancehead). This toxin is used in defibrinogenation and thrombolysis, and also has an effect on c-fos gene activity. Batrox
Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed;under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid;tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels;as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1;contains at least one functional […]